Universidad del País Vasco

Universidad del País Vasco

Bilbao
Spain


email Emilio J. Cocinero


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Universidad del País Vasco

Our research interests

Structural properties of molecules and clusters are interrogated by probing their electronic, vibrational and rotational energy levels using various spectroscopic methods: pulsed laser spectroscopy (nanosecond), high resolution rotational spectroscopy. Biological systems relevant to biomolecular building blocks are our targets, such as carbohydrates, peptides, glycopeptides as well as drugs for which structure-activity relationship and molecular recognition processes are key factors that govern their activity.

Selection of recent publications

- Ribose Found in the Gas Phase
Angew. Chem. Int. Ed., 51, pp. 3119-3124 (2012)

- Probing the C-H···π Weak Hydrogen Bond in Anesthetic Binding: The Gasphase Molecular Structure of the Sevoflurane-Benzene Cluster
Angew. Chem. Int. Ed., 53, pp.3210-3213 (2014)

- Sensing the anomeric effect in a solvent-free environment
Nature, 469, pp. 76-80 (2011)

Our expertise

- FTMW and CP-FTMW (Fourier transform Microwave spectroscopy)

- Electronic Laser Spectroscopy

Unité de Glycobiologie Structurale et Fonctionnelle

Unité de Glycobiologie Structurale et Fonctionnelle

Université de Lille - CNRS
France


email Fabrice Allain


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Unité de Glycobiologie Structurale et Fonctionnelle

Our research interests

At the UGSF, our team “Diversity of heparan sulfate (HS) and inflammatory responses” is working on the regulation of expression and activity of HS sulfotransferases, with the objective to elucidate the relations structure/function of these glycosaminoglycans in inflammatory and immune responses. We focus our interest on HS 3-Osulfafotransferases (HS3STs) and explore the mechanisms by which these enzymes generate functional HS structures in response to changes in cellular environment. We have also developed in vitro enzymatic assay for 3-O-sulfation, in order to produce HS mimetics that are closely related to 3-O-sulfated HS. These molecule will allow us to analyse the interaction between rare 3-O-sulfated motifs and their specific ligands.

Selection of recent publications

- Macrophage polarization alters the expression and sulfation pattern of glycosaminoglycans
Glycobiology, 25, pp.502-513 (2016)

- Molecular docking of heparin oligosaccharides with Hep-II heparinbinding domain of fibronectin reveals an interplay between the different positions of sulfate groups,
Glycoconj. J., 31, pp.161-169 (2014)

Our expertise

- Identification of rare and functional sulfated sequences (density and positions of sulfo groups) in heparan sulfates.

GlycoPedia

GlycoPedia


email Serge Perez


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GlycoPedia

Our research interests

The Glycopedia experience focuses on glycoscience based topics to popularize this scientific field and provides open access material to be used for educational purposes. It provides a portal to share news relevant to the community. They are multiform i.e. breaking news in the fields, ‘managerial’ type of news, new books...

Selection of recent publications

- The Symbolic Representation of Monosaccharides in the Age of Glycobiology

- NMR for Structural Glycoscience: I & II

- Gas Chromatography - Mass Spectrometry for Glycosciences

- In situ Physico-Chemical Characterization of Surface Confined Supramolecular Assemblies

- An Overview of Human Innate Immunity

- The Structure of Bacterial Cell Wall NB: Many chapters are written in the context of PhD thesis.

Our expertise

- 3D Visualization of Complex Carbohydrates, Polysaccharides and Glyco-Conjugates

- A Picture Dictionnary of Monosaccharide Symbols

- Library of Monosaccharide Templates. 1D, 2D, 3D Structures

- Library of Bio-active Monosaccharides. 1D, 2D, 3D Structures

- Online Databases & Tools

Institut Lumière Matière

Institut Lumière Matière

Université Lyon 1 - CNRS
France


email Isabelle Compagnon


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Institut Lumière Matière

Our research interests

At Institut Lumière Matière, we are specialized in the development of methods and instruments based on molecular physics for the structural characterization of biomolecules in the gas-phase. With the coupling of mass spectrometry with optical spectroscopy (IR, UV), we are able to retrieve the structure of unmodified oligosaccharides from natural or synthetic sources with atomistic resolution, using low amount of sample and minimal purification.

Selection of recent publications

- Anharmonic simulations of the vibrational spectrum of sulfated compounds: application to the glycosaminoglycan fragment glucosamine 6-sulfate,
Phys. Chem. Chem. Phys., 17, pp.25705-25713 (2015)

- Distinguishing isobaric phosphated and sulfated carbohydrates by coupling of mass spectrometry with gas phase vibrational spectroscopy,
Phys. Chem. Chem. Phys, 2014, 16, pp.22131-22138

Our expertise

- Analysis of monosaccharide content, stereochemistry, regiochemistry

- Analysis of functional modifications and sulfate patterns in glycosaminoglycans

ICBMS

Institut de Chimie et Biochimie Moléculaires et Supramoléculaires

Université Lyon 1 - INSA - CNRS
France


email Stephane Chambert


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Institut de Chimie et Biochimie Moléculaires et Supramoléculaires

Our research interests

In team COB of ICBMS, the Organic and Bioorganic Chemistry Laboratory at INSA-Lyon, we are interested in the design and synthesis of carbohydrate containing molecules. Between other projects, our research encompass the production of fluorescent glycoprobes for biological imaging as well as pure standards for infrared multiphoton analysis.

Selection of recent publications

- Anharmonic simulations of the vibrational spectrum of sulfated compounds: application to the glycosaminoglycan fragment glucosamine 6-sulfate,
Phys. Chem. Chem. Phys., 17, pp.25705-25713 (2015)

- Red Emitting Neutral Fluorescent Glycoconjugates for Membrane Optical Imaging.,
Bioconjugate Chem., 25, pp.773-787 (2014)

Our expertise

- Development of a fast analysis method for complex carbohydrate containing samples

ICBMS

Institut de Chimie et Biochimie Moléculaires et Supramoléculaires

Université Lyon 1 - INSA - CNRS
France


email Sébastien Vidal


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Institut de Chimie et Biochimie Moléculaires et Supramoléculaires

Our research interests

In Team CO2GLYCO, we design and synthesize glycoclusters as multivalent carbohydrate-coated molecules. The core structures used are calixarenes, pillararenes, fullerenes, porphyrins or resorcinarene. The synthetic strategy is based on azide-alkyne “click” chemistry and simple building blocks. The glycoclusters are then analyzed by NMR and mass spectrometry for their characterization and homogeneity. These glycoclusters are high affinity ligands of bacterial lectins and applications in antibacterial therapy in vivo has been demonstrated.

Selection of recent publications

- Pillar[5]arene-Based Glycoclusters: Synthesis and Multivalent Binding to Pathogenic Bacterial Lectins,
Chem. Eur. J.,22, pp.2955–2963 (2016)

- Glycomimetics versus Multivalent Glycoconjugates for the Design of High Affinity Lectin Ligands
Chem. Rev., 115, 525–561 (2015)

- Anti-adhesive properties of glycoclusters against Pseudomonas aeruginosa lung infection
J. Med. Chem., 57, 10275–10289 (2014)

Our expertise

- Some glycoclusters based on porphyrins are more difficult ot analyze by ESI-MS since the molecular ion was decomposed. MALDI-MS was the only technique possible and with strict conditions. A more universal technique and easily applicable would be useful.

ICBMS

Institut de Chimie et Biochimie Moléculaires et Supramoléculaires

Université Lyon 1 - INSA - CNRS
France


email Sylvie Ricard-Blum


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Institut de Chimie et Biochimie Moléculaires et Supramoléculaires

Our research interests

The team "Pericellular and Extracellular Supramolecular Assembly" builds and characterizes extracellular matrix interaction networks regulating angiogenesis, Alzheimer’s disease and host-pathogen interactions using in vitro and in silico approaches to decipher the molecular mechanisms involved. We focus on the structure, interactions and functions of multimolecular complexes anchored via glycosaminoglycans (GAGs) and syndecans in the pericellular matrix . We need new analytical tools for the analysis of sulfate patterns and iduronic acid level in cell and tissue glycosaminoglycans, analysis of glycosaminoglycan sequences, and standard bioinformatic tools for glycosaminoglycans

Selection of recent publications

- Launay et al. MatrixDB, the extracellular matrix interaction database: updated content, a new navigator and expanded functionalities.
Nucleic Acids Res, 43:D321-7 (2015)

- Peysselon & Ricard-Blum, Heparin-protein interactions: from affinity and kinetics to biological roles. Application to an interaction network regulating angiogenesis
Matrix Biol, 35:73-81 (2014)

- Fatoux-Ardore et al. Large-scale investigation of Leishmania interaction networks with host extracellular matrix by surface plasmon resonance imaging.
Infect Immun, 82:594-606 (2014)

- matrixdb.univ-lyon1.fr
MatrixDB, a protein-GAG interaction database

Our expertise

- Characterization of protein-protein and protein-GAG interactions by SPR and BioLayer Interferometry (kinetics, affinity) tissue glycosaminoglycans

- Curation of protein-protein and protein-GAG interactions

- MatrixDB (matrixdb.univ-lyon1.fr), a protein-GAG interaction database

- Topological and functional analysis of protein-protein and protein-GAG interaction networks

Centre de Recherche sur les Macromolécules Végétales

Centre de Recherche sur les Macromolécules Végétales

CNRS Grenoble
France


email Sébastien Fort


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Centre de Recherche sur les Macromolécules Végétales

Our research interests

The team Chemistry and Biotechnology of Oligosaccharides at CERMAV is specialized in the synthesis of oligo(poly)saccharides and glycoconjugates by chemical, enzymatic and microbial combined approaches Skills developed: CAZyme (Carbohydrate Active Enzymes) engineering, Metabolic engineering of microorganisms, Biocatalysis and Green Chemistry, Structural analysis

Selection of recent publications

- Efficient chemoenzymatic synthesis of lipo-chitin oligosaccharides as plant growth promoters,
Green Chem., 17(7), pp.3923-3930 (2015)

- Structure of an amino acid-decorated exopolysaccharide secreted by a Vibrio alginolyticus strain,
Mar. Drugs, 13(11), pp.6723-6739 (2015)

- Production of intracellular heparosan and derived oligosaccharides by lyase expression in metabolically engineered E. coli K-12
Carbohydr. Res., 360, pp.19-24 (2012)

Our expertise

- Analysis of neutral and charged oligo- and polysaccharides

Swiss Institute of Bioinformatics

Geneva
Switzerland


email Frédérique Lisacek


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Swiss Institute of Bioinformatics

Our research interests

The Proteome Informatics Group is involved in software and database development for the proteomics and the glycomics communities. The group focuses on mass spectrometry data analysis, the discovery of posttranslational modifications, and the functional study of glycoconjugates and carbohydrates.

Selection of recent publications

- MzJava: an open source mass spectrometry library
Horlacher O, Nikitin F, Alocci D, Mariethoz J, Müller M, Lisacek F (2015), J. Proteomics 129:63-70

- Graph Database vs RDF Triple Store: A Comparison on Glycan Substructure Search
Alocci D, Mariethoz J, Horlacher O, Bolleman JT, Campbell MP, Lisacek F (2015) PLoS One 10(12): e0144578

- SugarBindDB, a resource of glycan-mediated host-pathogen interactions
Mariethoz J, Khatib K, Alocci D, Campbell MP, Karlsson NG, Packer NH, Mullen EH, Lisacek F (2016) Nucleic Acids Res. 44(D1):D1243-50

Our expertise

- bioinformatics resource development

- mass spectrometry data analysis

- http://www.expasy.org/glycomics

Manchester Institute of Biotechnology

University of Manchester
UK


email Sabine L. Flitsch


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Manchester Institute of Biotechnology

Our research interests

Carbohydrates (such as sugars, glycans and polysachharides) provide the largest biomass on Earth and are central to many aspects of biotechnology. As such glycoscience and glycobiotechnology have broad applications in the development of biofuels, biomaterials and food stuffs from recycled and readily available biomass, as well as in medical research. Through investigation of the chemistry, structure and interactions associated with various carbohydrate molecules, it is possible to understand mechanisms of disease, develop novel glyco-based therapeutics and replicate the natural biosynthesis of glycans for synthetic purposes. However, the complex and diverse molecular nature of carbohydrates means that there is an urgent need to develop robust, wide-ranging synthetic and analytical methodologies for general use in this area. In the Flitsch lab. we have developed, and are continuing to expand, a toolbox for the synthesis and analysis of complex carbohydrates in order to understand their function.

Selection of recent publications

- Research article
P. Both, H. Busch, P. P. Kelly, F. G. Mutti, N. J. Turner, S. L. Flitsch, Sabine J. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION., 55; 1511 - 1513. DOI: 10.1002/anie.201510028 - JAN 22 2016

- Discrimination of epimeric glycans and glycopeptides using IM-MS and its potential for carbohydrate sequencing
Both, P.; Green, A. P.; Gray, C. J.; Sardzik, R.; Voglmeir, J.; Fontana, C.; Austeri, M.; Rejzek, M.; Richardson, D.; Field, R. A.; Widmalm, G.; Flitsch, S. L.; Eyers, C. E. NATURE CHEMISTRY. 6(1); 65 - 74. DOI 10.1038/NCHEM.1817 - JAN 2014

- Accelerated Enzymatic Galactosylation of N-Acetylglucosaminolipids in Lipid Microdomains
Noble, Gavin T.; Craven, Faye L.; Voglmeir, Josef; Sardzik, Robert; Flitsch, Sabine L.; Webb, Simon J. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY. 134(31); 13010 - 13017. DOI 10.1021/ja302506t - AUG 8 2012

- Chemoenzymatic Synthesis of O-Mannosylpeptides in Solution and on Solid Phase
- Sardzik, Robert; Green, Anthony P.; Laurent, Nicolas; Both, Peter; Fontana, Carolina; Voglmeir, Josef; Weissenborn, Martin J.; Haddoub, Rose; Grassi, Paola; Haslam, Stuart M.; Widmalm, Goran; Flitsch, Sabine L. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY. 134(10); 4521 - 4524. DOI 10.1021/ja211861m - MAR 14 2012

- Enzymatic Amine Acyl Exchange in Peptides on Gold Surfaces
Castangia, Roberto; Austeri, Martina; Flitsch, Sabine L. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION. 51(52); 13016 - 13018. DOI 10.1002/anie.201205404 - 2012

- Glycoprotein Labeling Using Engineered Variants of Galactose Oxidase Obtained by Directed Evolution
Rannes, Julie B.; Ioannou, Avgousta; Willies, Simon C.; Grogan, Gideon; Behrens, Carsten; Flitsch, Sabine L.; Turner, Nicholas J. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY. 133(22); 8436 - 8439. DOI 10.1021/ja2018477 - JUN 8 2011

Our expertise

- (i) glycoarrays to study glycoenzyme activity and discover carbohydrate-protein interactions

- (ii) ion mobility mass spectrometry for high resolution structural analysis of carbohydrates

- (iii) mass spectrometry for the label free identification of carbohydrate-binding proteins.

- (iv) chemoenzymatic synthesis of glycoconjugates (glycopeptides, glycolipids, etc.)

Institute of Integrative Biology

University of Liverpool
UK


email Claire Eyers


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Institute of Integrative Biology

Our research interests

Our main interests lie in the development and application of biochemical and biophysical (mass spectrometry, ion mobility) techniques to study cellular signalling (proteins and their modifications, and sugars) both qualitatively and quantitatively. Investigations into the behaviour and manipulation of these biomolecules (glycans, modified peptides, intact proteins) in the gas-phase and their analysis by ion mobility-mass spectrometry, allows us to better derive useful information on their structure and interactions, which is applied to systems of particular interest, two key examples being biologics (biological therapeutics) and the NF-κB signalling pathway. 

Selection of recent publications

- The power of ion mobility-mass spectrometry for structural characterization and the study of conformational dynamics
Lanucara F, Holman SW, Gray CJ, Eyers CE. Nat Chem. 2014 Apr;6(4):281-94. doi: 10.1038/nchem.1889.

- Discrimination of epimeric glycans and glycopeptides using IM-MS and its potential for carbohydrate sequencing
Both P, Green AP, Gray CJ, Sardzík R, Voglmeir J, Fontana C, Austeri M, Rejzek M, Richardson D, Field RA, Widmalm G, Flitsch SL, Eyers CE. Nat Chem. 2014 Jan;6(1):65-74. doi: 10.1038/nchem.1817

Our expertise

- qualitative and quantitative analysis of protein post-translational modifications

- glycan structural analysis by IM-MS

LAMBE

Université Evry Val d’Essonne - CNRS
France


email Régis Daniel


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LAMBE

Our research interests

* Structural and functional analysis of biomolecules (proteins, carbohydrates), more particularly focused on: - Proteins of the human complement system - Carbohydrate-using enzymes (Discovering and studies of new carbohydrate specific enzymes and biotechnological applications) - Structure/activity relationship of bioactive polysaccharide glycosaminoglycans (GAGs) and sulfated polysaccharides from marine algae (Roles of GAGs in the regulation of the innate immunity, Complement system). - Structural characterization of isomeric sugars through metal complexation. * Development of mass spectrometry hyphenated methods for deciphering information encoded in GAGs sequence, questioning the specificity of their molecular interactions, and probing structural determinants involved in their specific interaction with target proteins. - Affinity Capillary electrophoresis on-line coupled with ESI-MS - Surface Plasmon resonance coupled with MALDI-MS - Synchrotron X-Ray biomolecule footprinting coupled with ESI-MS - Liquid chromatography - Ion Mobility Mass spectrometry

Selection of recent publications

- MALDI-TOF MS and ESI-LTQ-Orbitrap tandem mass spectrometry reveal specific porphyranase activity from Pseudoalteromonas atlantica bacterial extract
RSC Advances 5: 80793-80803 (2015)

- Effects of Calcium complexation on Heparin-like disaccharide. A combined theoretical, MS/MS and UV experiments
, Rapid. Commun. Mass Spectrom. 29:1135-1144 (2015)

- Biomarkers probed in saliva by surface plasmon resonance imaging coupled to maldi mass spectrometry in array format
Anal. Bioanal. Chem. 407:1285–1294 (2015)

- Single Molecule Detection of Glycosaminoglycan Hyaluronic Acid Oligosaccharides and Depolymerization Enzyme Activity Using a Protein Nanopore
ACS Nano 6: 9672-9678 (2012).

- Probing the solution structure of Factor H using hydroxyl radical protein footprinting and cross-linking
Biochem. J., 2016, 473, 1805-1819.

- The chondroitin sulfate/dermatan sulfate 4-O-endosulfatase from marine bacterium Vibrio sp FC509 is a dimeric species: biophysical characterization of an endosulfatase
Biochimie, 2016, 131, 85-95.

- Efficient recovery of glycosaminoglycan oligosaccharides from polyacrylamide gel electrophoresis combined with mass spectrometry analysis
Anal. Bioanal. Chem., 2017 409(5),1257-1269

- SOLEIL shining on the solution-state structure of biomacromolecules by synchrotron X-ray footprinting at the Metrology beamline
J. Synchr. Rad., 2017 24, 576-585

Our expertise

- Capillary electrophoresis

- Surface Plasmon resonance on array biochips

- ion mobility-MS coupling

- Dynamic protein footprinting by X-ray synchrotron-mediated hydroxyl radical footprinting combined with high-resolution mass spectrometry

- Proteomics and Glycomics

- Biomolecular Interactions

- Mass spectrometry

LAMBE

Université Evry Val d’Essonne - CNRS
France


email Marie-Pierre Gaigeot


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LAMBE

Our research interests

DFT-MD (AIMD, FPMD) for theoretical anharmonic vibrational spectroscopy, CID, theoretical MS/MS Structure characterization from FPMD & theoretical spectrosocopy

Selection of recent publications
Our expertise

- DFT-based MD (DFT-MD)

- First-Principles MD (MD

- Ab initio MD (AIMD)

Bio-shape

Bio-shape Ltd.
UK


email Hannah Roberts


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Bio-shape

Our research interests

Bio-Shape has developed cutting edge technology based on mass spectrometry techniques that enables the analysis of biomolecules and their behaviours under stresses, in exquisite unprecedented detail and very quickly. OUR RESEARCH INTERESTS: Studying the structure-function relationships between carbohydrates and proteins using glycoarrays Sequencing carbohydrate structures Analysis of oligosaccharides extracted from fermentation waste for value added product streams Investigating the activity and selectivity of glycoenzymes Developing biocatalytic cascades, particularly for glycoconjugate synthesis and formal C-H amination Supporting the discovery and production of small molecule and protein-based therapeutics Investigation of ligand binding, conformational change, protein-protein interactions, aggregation, protein dynamics, binding stoichiometry, epitope mapping. Expertise in the analysis of monoclonal antibodies (mAbs) and their derivatives.

Selection of recent publications

- Dynamics of intact immunoglobulin G explored by drift-tube ion-mobility mass spectrometry and molecular modeling
DOI: 10.1002/anie.201402863

- Molecular Insights into the Thermal Stability of mAbs with Variable-Temperature Ion-Mobility Mass Spectrometry
DOI: 10.1002/cbic.201500574

- Discrimination of epimeric glycans and glycopeptides using IM-MS and its potential for carbohydrate sequencing
DOI: 10.1002/cbic.201500574

- Comprehensive stereochemical sequencing of carbohydrates using hyphenated mass spectrometry methods
BBA 2016 (Article in Press)

Our expertise

- Mass Spectrometry

- Ion Mobility Spectrometry

- Glycoarrays

- Glycoenzymes

Elicityl

Grenoble
France


email Benoît Darblade


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Elicityl

Our research interests

Based near Grenoble, France, ELICITYL is a biotech company devoted to complex sugar engineering and production.The company mission is to supply oligosaccharides and polysaccharides for biological applications targeting plant health, pharmacy, nutraceutics and cosmetics.

Selection of recent publications

- OligoTech®: a Library of complex carbohydrates & glycoproductsExtracted from biomassProduced by bacterial fermentationPotentially modified thru chemical functionalizationThe OligoTech® offer gives business opportunities using the untapped variety of complex sugars in compliance with all regulation appliances.

- Complex sugars for Plant health: ELICITYL commercialises PEL101GV®, a complex sugar extracted from biomass enhancing the natural vine resistance to spring frosts.

Our expertise

- Analytical tools

FELIX Laboratory

Institute for Molecules and Materials - Radboud University
Netherlands
 


email Jos Oomens


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FELIX Laboratory

Our research interests

Structural elucidation by IR ion spectroscopy of mass-selected species in MS, including their MSn reaction products. Our main focus is on molecules of biological interest, peptide fragmentation products, polyaromatic species of astrophysical interest and applications in bio-analytical chemistry

Selection of recent publications
Our expertise

- The FELIX free electron laser provides tunable, high intensity IR light at wavelengths between 3 and 150 mm. Tandem mass spectrometers available include FTMS and ion trap MS with ESI ion sources.

kth

KTH Biotechnology/Glycoscience Division

KTH Royal Institute of Technology

Stockholm, Sweden


email Francisco Vilaplana


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KTH Biotechnology/Glycoscience Division

Our research interests

Complex carbohydrates (‘glycans’ or ´polysaccharides’) are fundamental biomolecules responsible for many regulatory processes in life sciences. They constitute the main energy-reserve molecules and they provide structural stability in eukaryotic cell walls. Polysaccharides constitute moreover the main components of biomass and therefore the main renewable resource for human and animal nutrition, biofuels and material production. The structural heterogeneity of native polysaccharides at the different hierarchical levels is fundamental for their specific functionality in biological tissues; however, this structural complexity imposes major difficulties for their biotechnological exploitation. The complete structural determination of native polysaccharides at the molecular level is far from being implemented, as it is routinely done for the primary structure of nucleic acids and proteins. We are developing analytical tools for deciphering the molecular structure of complex biomass glycans (polysaccharides) using selective carbohydrate-active enzymes, multidimensional chromatography and mass spectrometry. This structural understanding can be directly related to their biosynthesis, remodeling and self-assembly in cell walls, their biological function, and their macroscopic properties (e.g. digestibility, solubility, aggregation, rheological and mechanical properties). This has fundamental implications for biomass deconstruction for biofuel production, for the design of functional carbohydrate-based materials, and for understanding the nutritional value of carbohydrate-rich foods. Our research interest include: (i) MS-based glycomic methods for carbohydrate structural elucidation (ii) Understand the molecular structure and supramolecular architecture of eukaryotic cell walls (plants and fungi) (iii) Application of carbohydrate-active enzymes in biomass processing ('biorefineries') (iv) Design of bioactive carbohydrate-based materials and additives. (v) Nutritional benefits of dietary polysaccharides

Selection of recent publications

- Sequential fractionation of feruloylated hemicelluloses and oligosaccharides from wheat bran using subcritical water and xylanolytic enzymes
Green Chemistry (2017), DOI: 10.1039/C6GC03473J

- Profiling the substitution pattern of xyloglucan derivatives by integrated enzymatic hydrolysis, hydrophilic-interaction liquid chromatography and mass spectrometry
Journal of Chromatography A (2016), 1463, 110-120

- A GH115 α-glucuronidase from Schizophyllum commune contributes to the synergistic enzymatic deconstruction of softwood glucuronoarabinoxylan
Biotechnology for Biofuels (2016) 9 2

- Two-Dimensional Size/Branch Length Distributions of a Branched Polymer
Macromolecules (2010) 43 7321

Our expertise
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